tiroid sintigrafisinde kullanılan 94,99,99m tc ve 131i radyonüklidlerinin Üretim tesir kesiti hesaplamaları

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ID: 230951
2014
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Abstract
Özet: Bu çalışmada, tiroid kanser metastazlarının görüntülenmesinde ve tedavisinde kullanılan 94,99,99mTc ve 131I radyonüklidlerinin üretim tesir kesiti incelenmiştir. Hesaplamalar, 94Mo(p,n)94Tc 100Mo(p,2n)99Tc, 98Mo(d,n)99mTc, 99Ru(n,p)99mTc ve 131Xe(n,p)131I reaksiyonları için 50 MeV parçacık gelme enerjisine kadar denge ve denge öncesi nükleer reaksiyon modelleri kullanılarak gerçekleştirilmiştir. Denge öncesi reaksiyonlar için; Full Exciton Model, Hibrit Model, Geometri Bağımlı Hibrit Model ve Cascade Exciton Model, denge reaksiyonları için ise; Weisskopf–Ewing Model kullanılmıştır. Ayrıca; 94,99,99mTc ve 131I üretimi için optimum enerji aralıkları ve bu enerjilerdeki ortalama tesir kesitleri belirlenmiştir. Anahtar kelimeler: Denge ve denge–öncesi reaksiyonlar, nükleer reaksiyon modelleri, tesir kesiti, radyonüklid Production Cross Section Calculations of 94,99,99mTc and 131I Radionuclides Used in Thyroid Scintigraphy Abstract: In this study, the production cross sections of 94,99,99mTc and 131I radionuclides used in imaging and treatment of thyroid cancer metastasis have been investigated. The calculations for 94Mo(p,n)94Tc 100Mo(p,2n)99Tc, 98Mo(d,n)99mTc, 99Ru(n,p)99mTc and 131Xe(n,p)131I reactions have been carried out up to 50 MeV incident particle energies by using the equilibrium and pre-equilibrium nuclear reaction models. Full Exciton Model, Hybrid Model, Geometry Dependent Hybrid Model, Cascade Exciton Model for the pre-equilibrium reactions and Weisskopf–Ewing Model for the equilibrium reactions have been used. Also, the optimum energy ranges and average cross sections in these energies for 94,99,99mTc and 131I production have been determined. Key Words: Equilibrium and pre–equilibrium reactions, nuclear reaction models, cross section, radionuclide
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Authors ;Yıldız Ergün;Abdullah Kaplan
Journal clinical chemistry
Year 2014
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