serum e3 sumo-protein ligase nse2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients

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ID: 229208
2017
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Abstract
Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ELISA. Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly decreased. Conclusions: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis.
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mehde2017asianserum Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Atheer Awad Mehde;Faridah Yusof;Wesen Adel Mehdi;Raha Ahmed Raus;Layla Othman Farhan;Jwan Abdulmohsin Zainulabdeen;Zaima Azira Zainal Abidin;Hamid Ghazali;Azlina Abd Rahman
Journal Organic letters
Year 2017
DOI
10.1016/j.apjtb.2016.12.008
URL
http://www.sciencedirect.com/science/article/pii/S2221169116302192
Keywords
nitric oxide peroxynitrite nephrolithiasis tropical medicinebiology (general)

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