synthesis and evaluation of anti-inflammatory, antioxidant and antimicrobial activities of densely functionalized novel benzo [d] imidazolyl tetrahydropyridine carboxylates

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ID: 229089
2017
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Abstract
A series of novel benzo[d]imidazolyl tetrahydropyridine carboxylates 7a–n have been synthesized by one-pot multi-component reaction of (E)-5-(benzylidene amino)-1H-benzo[d]imidazole-2-thiol 3, 5-amino-2-mercapto-benzimidazole 4, aromatic aldehyde 5, and ethyl acetoacetate 6 in acetonitrile using ceric ammonium nitrate (CAN) as Lewis acid catalyst, and evaluated for their anti-inflammatory, antioxidant, antibacterial and antifungal activities. All tested compounds showed appreciable activity against the standard drugs.
Reference Key
ravindernath2017arabiansynthesis Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Anisetti Ravindernath;Malladi Srinivas Reddy
Journal Behavioural brain research
Year 2017
DOI
10.1016/j.arabjc.2013.02.011
URL
http://www.sciencedirect.com/science/article/pii/S1878535213000439
Keywords
antioxidant anti-inflammatory ceric ammonium nitrate

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