molecular imaging in tumor angiogenesis and relevant drug research

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ID: 228268
2011
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Abstract
Molecular imaging, including fluorescence imaging (FMI), bioluminescence imaging (BLI), positron emission tomography (PET), single-photon emission-computed tomography (SPECT), and computed tomography (CT), has a pivotal role in the process of tumor and relevant drug research. CT, especially Micro-CT, can provide the anatomic information for a region of interest (ROI); PET and SPECT can provide functional information for the ROI. BLI and FMI can provide optical information for an ROI. Tumor angiogenesis and relevant drug development is a lengthy, high-risk, and costly process, in which a novel drug needs about 10–15 years of testing to obtain Federal Drug Association (FDA) approval. Molecular imaging can enhance the development process by understanding the tumor mechanisms and drug activity. In this paper, we focus on tumor angiogenesis, and we review the characteristics of molecular imaging modalities and their applications in tumor angiogenesis and relevant drug research.
Reference Key
ma2011internationalmolecular Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Xibo Ma;Jie Tian;Xin Yang;Chenghu Qin
Journal Chemistry, an Asian journal
Year 2011
DOI
10.1155/2011/370701
URL
http://dx.doi.org/10.1155/2011/370701
Keywords
Medicine (General) medical physics nuclear medicinemedical technology medical radiology

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