experimental poisoning by callaeum psilophyllum in rabbits and goats
intoxicação experimental por callaeum psilophyllum em coelhos e caprinos

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ID: 227717
2013
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Abstract
Callaeum (Mascagnia) psilophyllum is found in the same regions than Amorimia (Mascagnia) rigida, a sodium monofluoroacetate containing plant that cause sudden death associated with exercise in ruminants. With the objective to determine the toxicity of C. psilophyllum, leaves of the plant were administered to rabbits and goats. In rabbits doses of 6-12 g.kg-1 body weight caused tachycardia, dyspnea, and mydriasis. One rabbit, that ingested 10 g/kg, showed clinical signs similar to those caused by A. rigida in rabbits. Four goats showed diarrhea after the ingestion of green or dry leaves of the plant. Three died and one recovered. The results in rabbits suggest that C. psilophyllum contains fluoroacetate. However, clinical signs in goats suggest that C. psilophyllum contains another substance responsible for the digestive signs.

Callaeum (Mascagnia) psilophyllum é encontrada nas mesmas regiões que Amorimia (Mascagnia) rigida, uma planta que contêm monofluoroacetato de sódio e causa morte súbita associada ao exercício em ruminantes. Com o objetivo de determinar a toxicidade de C. psilophyllum, folhas desta planta foram administradas a coelhos e caprinos. Em coelhos, doses de 6-12 g.kg-1 de peso corporal causaram taquicardia, dispneia e midríase. Um coelho, que ingeriu 10 g.kg-1, apresentou sinais clínicos semelhantes aos causados por A. rigida em coelhos. Em caprinos, quatro animais apresentaram diarreia após a ingestão de folhas verdes ou secas da planta. Três caprinos morreram e um se recuperou. Os resultados em coelhos sugerem que C. psilophyllum contêm fluoroacetato. No entanto, os sinais clínicos em caprinos sugerem que C. psilophyllum contêm outra substância responsável pelos sinais digestivos.

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duarte2013semina:experimental Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Amélia Lizziane Leite Duarte;Rosane Maria Trindade Medeiros;Fabrício Kleber de Lucena Carvalho;Francelícia Pereira Marques Dantas;Anna Priscilla Moreira Figueiredo;Franklin Riet-Correa
Journal frontiers in neuroendocrinology
Year 2013
DOI
10.5433/1679-0359.2013v34n5p2363
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