the safety of antimicrobial drugs
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ID: 227694
2016
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Abstract
The discovery and introduction of antimicrobial drugs in clinical practice
has been recorded as one of the greatest achievements in the history of
medicine. The application of these drugs, made a big, almost revolutionary
upheaval in treatment of many infectious diseases. Its significance for the
humanity lies in the fact that hundreds of thousands of people, until then
condemned to a certain death, has been saved now. However, it was shown that
antimicrobial therapy carries some risk of possible occurrence of
undesirable and toxic effects, such as direct toxic effects, development of
resistance, the impact on the normal microflora or disorder of
micropopulation metabolic functions in digestive tract of ruminants,
unwanted interactions with other drugs, damage or necrosis of the tissue at
the injection site, residues in foodstuff intended for human consumption,
suppression of immune system or defense mechanisms of the body, and damage
of fetal or neonatal tissue. All mentioned, directly or indirectly, to a
greater or lesser degree can reduce the safety of these drugs.
| Reference Key |
vitomir2016veterinarskithe
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|---|---|
| Authors | ;Ćupić Vitomir;Jezdimirović Milanka;Dobrić Silva;Ivanović Saša;Ćupić-Miladinović Dejana |
| Journal | journal of instrumentation |
| Year | 2016 |
| DOI |
10.2298/VETGL1602059C
|
| URL | |
| Keywords |
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