Introduction: The present study aimed to test a model of the relationship between management commitment to safety and consciousness with unsafe performance,considering the mediating role of safety self-efficacy.  .Material and Method: Research design was the correlation throughStructural Equation Modeling (SEM) and the sampleconsisted of 265 employees of an industrialcompany who were selected by stratifiedrandom sampling method. Participants of this study completedsafety climatescale, short form of NEO personality questionnaire,safety self-efficacy scale, and unsafe performance questionnaire.Reliability and validity of the questionnaires were reported as acceptable. Evaluation of the proposed model was done by SEM through AMOS-21and SPSS-19 software packages. In addition, Preacher and Hayes’ SPSS Macro program was used for testing the mediating role.  .Result: The results showed that the proposedmodel fit the data properly.Management commitment to safety and consciousness had direct effect on unsafe performance and safety self-efficacy.Moreover, the mediating effect of safety self-efficacy in the relationship between management commitment to safety and consciousness with unsafe performancewas confirmed. . Conclusion: Overall, organizations canreduce unsafe performance and consequently occupational accidentsby increasing the management commitment to safety and employees’ consciousness and also training of employees and supervisors to reinforce their safety self-efficacy.