prevalence and factors associated with mycobacteremia and mortality among febrile hiv infected patients in mwanza, tanzania

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ID: 225601
2018
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Abstract
Objectives: This study investigated the prevalence and factors associated with mycobacteremia and mortality among febrile HIV infected patients in developing countries. Methods: A hospital based cross-sectional study was conducted among febrile HIV patients admitted at Bugando Medical centre and Sekou Toure hospital between November 2016 and March 2017. Blood culture was done on BACTEC Myco/F Lytic bottles. Clinical and demographic data were collected using a pre-tested data collection tool. Results: A total of 154 patients with the mean age of 41.5 ± 12.2 were enrolled. Females formed the majority, 93 (60%) of the study participants. The prevalence of Mycobacteremia was 3.3% while that of other bacteria was 8.4%. Age (p = 0.03), recent HIV diagnosis (p = 0.005), not taking HAART (p = 0.031) and low CD4+ count (p = 0.002) were significantly associated with Mycobacteremia. Factors significantly associated with 14-day in-hospital mortality were advanced HIV infection (p < 0.001), poor ART adherence (p < 0.001), low CD4+ (p = 0.0002) and Mycobacteremia (p = 0.007). Conclusion: The prevalence of Mycobacteremia was low; however, it was significantly associated with mortality. Mycobacteremia should be suspected in high risk febrile HIV infected individuals followed by early appropriate treatment in order to reduce associated morbidity and mortality. Keywords: Mycobacteremia, Mortality, Fever, HIV
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manyiri2018internationalprevalence Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Paulina Manyiri;Rodrick Kabangila;Christa Kasang;Martha F. Mushi;Mariam M. Mirambo;Stephen E. Mshana
Journal israel journal of chemistry
Year 2018
DOI
DOI not found
URL
http://www.sciencedirect.com/science/article/pii/S1201971218300687
Keywords
Infectious and parasitic diseases

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