modern medicamentous treatment of epilepsy in adults

Clicks: 17
ID: 225093
2006
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Abstract

Background: Several »newer« antiepileptic drugs (AEDs), i.e. vigabatrin, lamotrigine, gabapentin, topiramate, tiagabine, oxcarbazepine, levetiracetam, pregabalin and zonisamide have been introduced into clinical practice within the last decade. Most of these new drugs are at least as effective as the »older« AEDs (phenobarbital, phenytoin, valproic acid, carbamazepine) and in general, they seem to be better tolerated then the older drugs and have less side effects. The development of pharmaceutical industry has brought several new AEDs to clinical practice which increased a probability of therapeutic success, but also made treatment more complex. It is expected from the physician that she will know indications and contraindications for at least 15 AEDs, their optimal titration, dosage, possible side effects and wide spectrum of interactions with other drugs. At this point advertisements of drug companies try to convince us aggressively about success of their own products.

Conclusions: This review article focuses on modern medicamentous treatment of adults with epilepsy, main characteristics of newer AEDs, conditions, availability and statistics of their usage in Slovenia.

Reference Key
zgonc2006zdravnikimodern Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Vid Zgonc;Boštjan Čebular
Journal planta medica
Year 2006
DOI
DOI not found
URL
http://vestnik.szd.si/index.php/ZdravVest/article/view/2015
Keywords
epilepsy

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