autólise da camada de células granulares do cerebelo em bovinos conglutination of the cerebellar granule cell layer in cattle

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ID: 224279
2008
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Abstract
A autólise da camada de células granulares do cerebelo é um achado postmortem observado em bovinos e relacionado ao prolongado tempo de duração entre a morte e a fixação do encéfalo. Para observar a prevalência desse artefato, 228 cerebelos foram examinados histologicamente ao longo do verme cerebelar. Trinta e seis por cento desses casos apresentaram conglutinação cerebelar não relacionada a doença específica. Em 74,4% dos casos em que foi observada conglutinação cerebelar, não foram observadas alterações histopatológicas. Histologicamente, a conglutinação cerebelar caracterizou-se por dissolução segmentar ou difusa da camada de células granulares. A descrição deste artefato é importante, pois já foi confundido como lesão relacionada a doença específica do sistema nervoso de bovinos.
Cerebellar conglutination of the granule cell layer is a postmortem artifact observed in cattle. It is related to increased time between death and fixation of the brain. In this study, 228 cerebellum were histologically analyzed throughout cerebellar vermis. Cerebellar conglutination was observed in 36% of the cases and it was not related to specific diseases. Seventy-four percent of the cases did not present any histological lesions in the brain. Microscopically, cerebellar conglutination was characterized by segmentar or diffuse dissolution of the granule cell layer. This artifact has been misinterpreted as resulting from specific diseases of the central nervous system in cattle, and it has to be differentiated from important antemortem lesions.
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Authors Raquel Rubia Rech, Daniel Ricardo Rissi, Felipe Pierezan, Adriane Loy Gabriel, Claudio Severo Lombardo de Barros
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Journal Trials
Year 2008
DOI
10.1590/S0103-84782008000400048
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000400048
Keywords
central nervous system pathology neuropathology

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