parasitological characteristics of schistosoma mansoni infection in swiss mice with underlying malnutrition
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ID: 223710
2002
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Abstract
The effects of a protein-restricted diet (8% protein, 81% carbohydrate and 11% lipids) on Schistosoma mansoni infectivity, fecal egg excretion and intestinal egg distribution in Swiss (SW) mice were studied. Pregnant mice received a deficient diet from the middle of gestation until delivery. Seven-days-old mice were exposed to 50 cercariae (BH strain, Brazil). Offspring mice had a free access to the deficient diet since lactation until adulthood. The controls were fed with a commercial mice diet. A parasitological examination was performed between six and eight weeks post-infection while both groups were necropsied one week later. Mice on the experimental diet showed a significant loss in body weight. There was no significant difference (p > 0.05) in pre-patent period, kinetics of egg excretion and worm recovery from mice on either diet. Significant differences (p < 0.05) were found concerning to the percentage of deposited eggs in the distal segment of the small intestine from hosts on the experimental diet.Our data suggest that experimental malnutrition induced for a long term has no detrimental effect on the acute schistosomiais infection in SW mice.
| Reference Key |
simes2002memriasparasitological
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|---|---|
| Authors | ;Carla Simões;Renata Heisler Neves;Lucas de Andrade Barros;Patrícia Dias Brito;Cristiane Oliveira Cravo;Egberto Gaspar de Moura;José Roberto Machado-Silva |
| Journal | kurdistan journal of applied research |
| Year | 2002 |
| DOI |
10.1590/S0074-02762002000900027
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| URL | |
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