exclusive phlebosclerosis of submucosal veins leading to ischemic necrosis and perforation of the large bowel: first european case
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ID: 222377
2018
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Abstract
Phlebosclerotic colitis (PC) is a rare, potentially life-threatening disease of unclear pathogenesis almost exclusively reported in Asian patients of both genders. A fibrous degeneration of venous walls leads to threadlike calcifications along mesenteric vessels and colonic wall thickening, detectable by CT. This causes disturbed blood drainage and hemorrhagic infarction of the right-sided colonic wall. This is a report of PC in a Caucasian woman in Europe without Asian background and no history of herbal medications, a suspected cause in Asian patients. CT revealed no calcification of the mesenteric vein or its tributaries. Instead, submucosal veins of the left-sided colonic wall were calcified, leading to subsequent transmural necrosis. Clinically, the patient developed a paralytic ileus and sigmoidal perforation during a 2-week hospitalization due to a bleeding cerebral vascular aneurysm. This case of a European woman with PC is unique in its course as well as its radiologic, clinical, and pathologic presentation.
| Reference Key |
klein2018caseexclusive
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|---|---|
| Authors | ;Sebastian Klein;Denise Buchner;De-hua Chang;Reinhard Büttner;Uta Drebber;Jochen W.U. Fries |
| Journal | trends in genetics : tig |
| Year | 2018 |
| DOI |
10.1159/000488195
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| URL | |
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