retinoids and cardiac development

Clicks: 247
ID: 222243
2014
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Abstract
Retinoic acid (RA), a derivative of vitamin A, is involved in signal transduction during vertebrate organogenesis. Retinoids through binding to nuclear receptors called RA receptors (RARs) and retinoid X receptors (RXRs) regulate various processes during cardiogenesis. Deregulated retinoid signaling thus has later consequences leading to cardiac malformations. In this review, we will summarize and discuss our current knowledge on the role of RA signaling during heart development, especially during patterning of the heart fields. We have also integrated recent experiments essential for our understanding of the role of RA signaling during epicardial development and myocardial growth.
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zaffran2014journalretinoids Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Stéphane Zaffran;Nicolas El Robrini;Nicolas Bertrand
Journal journal of counseling psychology
Year 2014
DOI
10.3390/jdb2010050
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