computational analysis of pumping efficacy of a left ventricular assist device according to cannulation site in heart failure with valvular regurgitation

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ID: 222167
2016
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Abstract
Mitral valve regurgitation (MR) causes blood to flow in two directions during contraction of the left ventricle (LV), that is, forward into the aorta and backward into the left atrium (LA). In aortic valve regurgitation (AR), leakage occurs from the aorta into the LV during diastole. Our objective is to analyze the contribution of a left ventricular assist device (LVAD) to MR and AR for the following two different cannulation sites: from the LA to the aorta (LAAO) and from the LV to the aorta (LVAO). Using a computational method, we simulated three ventricular conditions (normal [HF without valvular regurgitation], 5% MR, and 5% AR) in three groups (control [no LVAD], LAAO, and LVAO). The results showed that LVAD with LAAO cannulation is appropriate for recovery of the MR heart, and the LVAD with LVAO cannulation is appropriate for treating the AR heart.
Reference Key
heikhmakhtiar2016computationalcomputational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Aulia Khamas Heikhmakhtiar;Ki Moo Lim
Journal advanced functional materials
Year 2016
DOI
10.1155/2016/6930482
URL
http://dx.doi.org/10.1155/2016/6930482
Keywords
medical informatics computer applications to medicine

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