detection of anti-ige anti-fcεri α chain auto-antibodies in patients with atopic dermatitis
Cliques: 188
ID: 221494
2000
Metricas de Qualidade e Desempenho do Artigo
Qualidade Geral
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Engajamento do Leitor
Popular Article
30.0
/100
188 visualizacoes
26 leitores
Avaliacao de Qualidade por IA
Nao analisado
Readership in this journal
PopularRanked #87 of 108 articles by views in current drug discovery technologies
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Resumo
Anti-IgE and anti-FcεRI α chain auto-antibodies have been detected in the sera of atopic and non-atopic subjects; however, the biological activity of these auto-antibodies is still unclear. These two kinds of autoantibodies were examined in atopic dermatitis (AD) patients. In results, 12 of 92 AD patients have the anti-IgE, eight have the anti-FcεRI α auto-antibodies and two have both auto-antibodies. Furthermore, biological characterization of these auto-antibodies has been performed. In results, three of 12 samples with the anti-IgE auto-antibodies exhibited inhibitory activity for IgE-FcεRI α binding. Two of the eight samples with the anti-FcεRI α auto-antibodies and one of the two samples with both auto-antibodies had histamine releasing activity. It is documented here that both anti-IgE and anti-FcεRI α auto-antibodies were detected in some AD patients, some anti-IgE auto-antibodies had inhibitory activity for IgE-FcεRI binding and also histamine releasing activity was detected in the anti-FcεRI α chain auto-antibody.
| Chave de Referencia |
hayashi2000allergologydetection
Use esta chave para citacao automatica no manuscrito ao usar
SciMatic Gerenciador de Manuscritos ou Gerenciador de Teses
|
|---|---|
| Autores | ;Satoru Hayashi;Hajime Suto;Naruhito Wada;Hideoki Ogawa;Ko Okumura;Chisei Ra |
| Periodico | current drug discovery technologies |
| Ano | 2000 |
| DOI |
10.1046/j.1440-1592.2000.00158.x
|
| URL | |
| Palavras-chave |
Citacoes
Nenhuma citacao encontrada. Para adicionar uma citacao, entre em contato com o administrador em info@scimatic.org
Comentarios
Nenhum comentario ainda. Seja o primeiro a comentar neste artigo.