generation of kcl012 research grade human embryonic stem cell line carrying a mutation in the htt gene
Clicks: 133
ID: 220027
2016
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
133 views
25 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #101 of 117 articles by views in journal of energy chemistry
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro and in vivo assays.
| Reference Key |
jacquet2016stemgeneration
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Laureen Jacquet;Heema Hewitson;Victoria Wood;Neli Kadeva;Glenda Cornwell;Stefano Codognotto;Carl Hobbs;Emma Stephenson;Dusko Ilic |
| Journal | journal of energy chemistry |
| Year | 2016 |
| DOI |
10.1016/j.scr.2016.01.012
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.