secondary bilateral angle closure glaucoma due to topiramate

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ID: 219263
2011
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Abstract
We examined a 39-year-old female with severe headache and blurred vision. She was on topiramate, 50 mg once a day for one week because of migraine. Periorbital edema, chemosis, myopia, high intraocular pressures, and shallow anterior chambers were present at the initial examination. Iridocorneal angles were closed, ultrasound showed choroidal effusions. We stopped topiramate and started antiglaucoma treatment. After one week the intraocular pressure was 10 mm Hg in both eyes without treatment. A new ultrasound showed no choroidal effusions. Topiramate has been associated with acute secondary angle closure glaucoma as an idiosyncratic reaction to the drug. Physicians prescribing topiramate need to alert patients of this potential sight-threatening idiosyncratic reaction.
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paciuc-beja2011casesecondary Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Miguel Paciuc-Beja;Myriam Retchkiman-Bret;Cecilio Francisco Velasco-Barona;Victor Hugo Galicia-Alfaro
Journal hastings center report
Year 2011
DOI
10.1155/2011/594051
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