consequences of the magnetic field, sonic and radiofrequency waves and intense pulsed light on the labeling of blood constituents with technetium-99m

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ID: 217876
2007
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Abstract
Sources of magnetic field, radiofrequency and audible sonic waves and pulsed light have been used in physiotherapy to treat different disorders. In nuclear medicine, blood constituents(Bl-Co) are labeled with technetium-99m (99mTc) are used. This study evaluated the consequences of magnetic field, radiofrequency and audible sonic waves and intense pulsed light sources on the labeling of Bl-Co with 99mTc. Blood from Wistar rats was exposed to the cited sources. The labeling of Bl-Co with 99mTc was performed. Blood not exposed to the physical agents was used(controls). Data showed that the exposure to the different studied sources did not alter significantly (p>0.05) the labeling of Bl-Co. Although the results were obtained with animals, the data suggest that no alteration on examinations performed with Bl-Co labeled with 99mTc after exposition to the cited agents. The biological consequences associated with these agents would be not capable to interfere with some properties of the Bl-Co.
Fontes de campo magnético, ondas sonoras audíveis e de radiofreqüência e luz intensa pulsada são usadas para o tratamento de doenças. Constituintes sangüíneos(CS) marcados com tecnécio-99m(99mTc) são utilizados na medicina nuclear. Esse trabalho avaliou as consequências de fontes de campo magnético, ondas sonoras audíveis e de radiofreqüência e luz intensa pulsada na marcação de CS com 99mTc. Sangue de ratos Wistar foi exposto às fontes citadas. A marcação de CS com 99mTc foi realizada. Sangue não exposto foram utilizadas(controle). Resultados mostraram que os agentes físicos estudados não alteraram significativamente (p>0.05) a radiomarcação de CS. Apesar terem sido obtidos com sangue de animais, os resultados sugerem que nenhuma alteração nos exames realizados com constituintes sangüíneos com 99mTc em medicina nuclear ocorreria após a exposição às fontes avaliadas. As consequências biológicas associadas a esses agentes não seriam capazes de interferir com algumas propriedades dos CS.
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Authors ;Patricia Froes Meyer;Sebastião David Santos-Filho;Oscar Ariel Ronzio;Ludmila Bonelli;Adenilson de Souza da Fonseca;Iris do Ceu Clara Costa;José Brandão Neto;Aldo da Cunha Medeiros;Mario Bernardo-Filho
Journal current drug delivery
Year 2007
DOI
10.1590/S1516-89132007000600014
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600014
Keywords
magnetic field

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