Validation of the Quantitative Checklist for Autism in Toddlers in an Italian Clinical Sample of Young Children With Autism and Other Developmental Disorders.

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ID: 21684
2019
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Ranked #39 of 77 articles by views in Frontiers in psychiatry

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Abstract
The Quantitative Checklist for Autism in Toddlers (Q-CHAT) is parent-report screening questionnaire for detecting threshold and sub-threshold autistic features in toddlers. The Q-CHAT is a dimensional measure normally distributed in the general population sample and is able to differentiate between a group of children with a diagnosis of autism and unselected toddlers. We aim to investigate the psychometric properties, score distribution, and external validity of the Q-CHAT in an Italian clinical sample of young children with autism versus children with developmental delay and typically developing children. N = 126 typically developing children (TD), n = 139 children with autism, and n = 50 children presenting developmental delay (DD) were administered the Q-CHAT. Standardized measures of cognitive functions, language, and behaviors were also obtained. The Q-CHAT scores were normally distributed and demonstrated adequate internal consistency and good item to total score correlations. The mean Q-CHAT score in the autism group was significantly higher than those found in the DD sample and TD children. No difference on the mean Q-CHAT score between DD and TD children was found. The accuracy of the Q-CHAT to discriminate between autism and TD was very good. Two different cut-points (27 and 31, respectively) maximized sensitivity and specificity for autism versus TD and DD, respectively. Finally, higher Q-CHAT scores were correlated with lower language and social communication skills. In clinical settings, the Q-CHAT demonstrated good psychometric properties and external validity to discriminate autism children not just from children with typical development but also from children with developmental delay.
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Authors Ruta, Liliana;Chiarotti, Flavia;Arduino, Giuseppe Maurizio;Apicella, Fabio;Leonardi, Elisa;Maggio, Roberta;Carrozza, Cristina;Chericoni, Natasha;Costanzo, Valeria;Turco, Nazarena;Tartarisco, Gennaro;Gagliano, Antonella;Allison, Carrie;Baron Cohen, Simon;Pioggia, Giovanni;Muratori, Filippo;
Journal Frontiers in psychiatry
Year 2019
DOI
10.3389/fpsyt.2019.00488
URL
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