changes in the interpretation of the results of susceptibility testing of fungi

The incidence of fungal infections is increasing together with the growing number of immunocompromised patients. For successful treatment it is necessary to select the optimal dose of a specific antifungal agent based on the in vitrosusceptibility testing according to the microdilution method by CLSI (Clinical and Laboratory Standards Institute) or EUCAST (European Committee on Antimicrobial Susceptibility Testing). All of the susceptibility testing results in Slovenia were processed and interpreted according to CLSI, but gradually we will start using the EUCAST system, which brings certain differences in methodology that shorten the incubation time by 24 hours and bring some changes in the interpretation of MICs (Minimal Inhibitory Concentration).