citologia de impressão conjuntival em crianças desnutridas graves hospitalizadas conjunctival impression cytology in children hospitalized with severe malnutrition

Clicks: 329
ID: 216150
2010
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Abstract
OBJETIVOS: avaliar os achados da citologia de impressão conjuntival (CIC) em crianças com desnutrição energético protéica (DEP) grave, hospitalizadas no Instituto de Medicina Integral Prof. Fernando Figueira (IMIP). MÉTODOS: estudo descritivo, tipo série de casos, realizado no período de agosto de 2005 a maio de 2006, envolvendo 41 crianças de um a 60 meses, com desnutrição grave (peso/altura < -3DP e/ou edema - padrão NCHS). A técnica para a realização da CIC seguiu normas padronizadas segundo estudo de validação. A leitura das lâminas foi realizada por dois observadores independentes. RESULTADOS: a idade dos casos variou de um a 47 meses, com a mediana de nove meses. Observou-se padrão de anormalidade da CIC em 46,3% das crianças. Entre os casos com CIC anormal (marginal (-) e deficiente), 40% apresentaram edema. CONCLUSÕES: a prevalência elevada de resultados anormais de CIC, resumindo as classificações marginal (-) e padrão deficiente, justifica, na experiência aqui relatada, o cuidado normativo de se utilizar doses elevadas de vitamina A no tratamento hospitalar de desnutridos graves.
OBJECTIVES: to evaluate conjunctival impression cytology (CIC) findings in children hospitalized with severe energy protein malnutrition at the Instituto de Medicina Integral Prof. Fernando Figueira (IMIP). METHODS: a descriptive case series study was carried out between august 2005 and may 2006 with 41 children aged between 1 and 60 months with severe malnutrition (weight/height < -3DP and/or edema -NCHS standard). The CIC technique used followed the standard norms established by the validation study. The slides were examined by two independent observers. RESULTS: the age of cases varied from one to 47 months, with a median of nine months. An abnormal CIC pattern was observed in 46.3% of children. Forty percent of cases of abnormal CIC (marginal (-) and deficient), also presented edema. CONCLUSIONS: the high prevalence of abnormal CIC results found here justifies the standard treatment of high doses of vitamin A for cases of severely malnourished children admitted to hospital.
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Authors ;Larissa Albuquerque Paiva;Ana Rodrigues Falbo;Maria de Fátima Costa Caminha;Margarida Maria de Freitas Lola;Ilma Kruze Grande de Arruda;Malaquias Batista Filho
Journal sociology
Year 2010
DOI
10.1590/S1519-38292010000300004
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292010000300004
Keywords
cytology vitamin a deficiency

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