antimicrobial activity of some thiourea derivatives and their nickel and copper complexes

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ID: 215817
2009
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Abstract
Five thiourea derivative ligands and their Ni2+ and Cu2+ complexes have been synthesized. The compounds were screened for their in vitro anti-bacterial activity using Gram-positive bacteria (two different standard strains of Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Streptococcus pyogenes, Bacillus cereus) and Gram-negative bacteria (Esherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae, Proteus vulgaris, Enterobacter aerogenes) and in vitro anti-yeast activity (Candida albicans, Candida krusei, Candida glabrata, Candida tropicalis, Candida parapsilosis). The minimum inhibitory concentration was determined for all ligands and their complexes. In vitro anti-yeast activity of both ligands and their metal complexes is greater than their in vitro anti-bacterial activity. The effect of the structure of the investigated compounds on the antimicrobial activity is discussed.
Reference Key
akbay2009moleculesantimicrobial Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Cevdet Akbay;Cemal Koray Ozer;Gulay Borekci;Nizami Duran;Hakan Arslan
Journal Journal of ethnopharmacology
Year 2009
DOI
10.3390/molecules14010519
URL
http://www.mdpi.com/1420-3049/14/1/519/
Keywords
Antifungal Activity antibacterial activity complexes in vitro studies

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