intracranial rosai-dorfman disease

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ID: 215681
2012
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Ranked #124 of 133 articles by views in 2017 ieee international conference on communication, networks and satellite, comnetsat 2017 - proceedings

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Abstract
Rosai-Dorfman disease is a benign lymphohistiocytosis that often involve lymph nodes and present as massive lymphadenopathy with sinus histiocytosis. The disease is rarely associated with intracranial involvement. Herein, we report a 33-years-old man with recent onset of unconsciousness. According to his past medical history, he was suffering from frontal headache, ataxia and dizziness with no sensory or motor defect since August 2010. At initial work up, MRI showed infiltrating mass in the left parietal region. Microscopically, the mass consisted of infiltration of abundant lymphoplasma cells, neutrophils and some histiocytes scattered in fibrotic background. Emperipolesis (lymphocytophagocytosis) of histiocytic cells made the diagnosis of Rosai-Dorfman disease. Rosai-Dorfman disease should be added in the list of differential diagnosis for a dural mass mimicking meningioma or cerebral mass mimicking glioma, therefore, immunohistochemical staining for EMA, S100 and CD1a should be performed to rule out the differential diagnosis.
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mahzoni2012journalintracranial Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Parvin Mahzoni;Mohsen Hani Tabaei Zavareh;Marzie Bagheri;Neda Hani;Babak Moqtader
Journal 2017 ieee international conference on communication, networks and satellite, comnetsat 2017 - proceedings
Year 2012
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