n-butyl cyanoacrylate synthesis. a new quality step using microwaves

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ID: 213720
2014
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Abstract
Alkyl cyanoacrylates are interesting products for use in industry because of their properties enabling them to stick together a wide range of substrates. n-Butyl cyanoacrylate is one of the most successfully used tissue adhesives in the field of medicine because it exhibits bacteriostatic and haemostatic characteristics, in addition to its adhesive properties. At present, its synthesis is performed with good yields via Knoevenagel condensation using conventional sources of heating, but this requires a long processing time. The aim of this work was to look for a new way of synthesising n-butyl cyanoacrylate using microwave irradiation as the source of heating. This non-conventional source of heating most likely reduces the process time of the synthesis. In comparison with a conventional heating source, such as an oil bath, the results showed the advantages of this method whereby the n-butyl cyanoacrylate gave the same yield and quality with a reduction in the reaction time by a factor of 3-5-fold.
Reference Key
carriles2014moleculesn-butyl Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Yaquelin Ramos Carriles;Rubén Álvarez Brito;Ricardo Martínez Sánchez;Elayma Sánchez Acevedo;Paola Rodríguez Domínguez;Wolf-Dieter Mueller
Journal Journal of ethnopharmacology
Year 2014
DOI
10.3390/molecules19056220
URL
http://www.mdpi.com/1420-3049/19/5/6220
Keywords Keywords not found

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