hemogasometria em cães com desidratação experimental tratados com soluções eletrolíticas comerciais administradas por via intravenosa blood gas analysis in dogs with experimental dehidration treated with commercial electrolytes solutions by intravenous route

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ID: 213493
2008
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Abstract
No presente estudo, foram comparados os efeitos da administração intravenosa de três soluções eletrolíticas comerciais sobre o equilíbrio ácido-base em cães desidratados experimentalmente por restrição hídrica e poliúria. Os animais foram aleatoriamente distribuídos em três grupos e tratados com três diferentes soluções eletrolíticas comerciais durante 12 horas: Ringer com lactato de sódio (RL), Ringer simples (RS) e Glicofisiológico (GF). Entre os tratamentos testados, a fluidoterapia intravenosa com solução de Ringer com lactato de sódio (RL) foi o tratamento que apresentou efeito alcalinizante, sinalizado por pequeno aumento nos valores do pH(a), cHCO3(aP), ctCO2(aP) e cBase(a), podendo ser utilizada no tratamento de animais com acidose metabólica de intensidade discreta a moderada. As soluções Ringer simples (RS) e glicofisiológica (GF) determinaram discreta diminuição na concentração de base titulável do sangue arterial (cBase), demonstrando efeito acidificante, o que as tornam uma opção para tratar cães com alcalose metabólica.
Three commercial intravenous electrolyte solutions were compared as for their effects on the blood acid-base status in dogs experimentally dehydrated by withholding water and inducing polyuria. Animals were randomly divided into three groups which were rehydrated with the following commercial electrolyte solutions during 12 hours: Lactate Ringer´s solution (RL), Ringer´s solution (RS) and a normal saline solution (0.9% sodium chloride) containing 5% dextrose (GF). The RL´s intravenous fluid therapy resulted in an alkalinizing effect demonstrated by a mild increase in arterial blood pH, ctCO2, bicarbonate (cHCO-3), and arterial blood base concentration (cBase) and, thus, can be used in animals exhibiting mild to moderate metabolic acidosis. In contrast, the RS and GF therapies led to a mild decrease in the concentration of arterial blood tritiable base (cBase) inducing an acidifying effect, which make them an option to treat dogs with metabolic alkalosis.
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Authors ;José Dantas Ribeiro Filho;Paula de Zorzi Balbinot;José Antônio Viana;Waleska de Melo Ferreira Dantas;Betânia Souza Monteiro
Journal Trials
Year 2008
DOI
10.1590/S0103-84782008000700017
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000700017
Keywords
dogs blood gas analysis fluid therapy

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