hpvpdb: an online proteome reserve for human papillomavirus

Clicks: 318
ID: 213345
2013
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Abstract
Human papillomavirus (HPV) infection is the leading cause of cancer mortality among women worldwide. The molecular understanding of HPV proteins has significant connotation for understanding their intrusion in the host and designing novel protein vaccines and anti-viral agents, etc. Genomic, proteomic, structural, and disease-related information on HPV is available on the web; yet, with trivial annotations and more so, it is not well customized for data analysis, host-pathogen interaction, strain-disease association, drug designing, and sequence analysis, etc. We attempted to design an online reserve with comprehensive information on HPV for the end users desiring the same. The Human Papillomavirus Proteome Database (hpvPDB) domiciles proteomic and genomic information on 150 HPV strains sequenced to date. Simultaneous easy expandability and retrieval of the strain-specific data, with a provision for sequence analysis and exploration potential of predicted structures, and easy access for curation and annotation through a range of search options at one platform are a few of its important features. Affluent information in this reserve could be of help for researchers involved in structural virology, cancer research, drug discovery, and vaccine design.
Reference Key
kumar2013genomicshpvpdb: Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Satish Kumar;Lingaraja Jena;Sangeeta Daf;Kanchan Mohod;Peyush Goyal;Ashok K. Varma
Journal Journal of environmental management
Year 2013
DOI
10.5808/GI.2013.11.4.289
URL
http://genominfo.org/upload/pdf/gni-11-289.pdf
Keywords
neoplasms hpv genome dna probes

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