upregulation of hsa-mir-125b in htlv-1 asymptomatic carriers and htlv-1-associated myelopathy/tropical spastic paraparesis patients
Clicks: 281
ID: 213099
2012
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Emerging Content
30.0
/100
281 views
67 readers
AI Quality Assessment
Not analyzed
Readership in this journal
EmergingRanked #90 of 450 articles by views in kurdistan journal of applied research
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 450 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
The retrovirus human T lymphotropic virus type 1 (HTLV-1) promotes spastic paraparesis, adult T cell leukaemia and other diseases. Recently, some human microRNAs (miRNAs) have been described as important factors in host-virus interactions. This study compared miRNA expression in control individuals, asymptomatic HTLV-1 carriers and HTLV-1 associated myelopathy (HAM)/tropical spastic paraparesis patients. The proviral load and Tax protein expression were measured in order to characterize the patients. hsa-miR-125b expression was significantly higher in patients than in controls (p = 0.0285) or in the HAM group (p = 0.0312). Therefore, our findings suggest that miR-125b expression can be used to elucidate the mechanisms of viral replication and pathogenic processes.
| Reference Key |
nicolete2012memriasupregulation
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Larissa Deadame de Figueiredo Nicolete;Roberto Nicolete;Rodrigo Haddad;Rochele Azevedo;Fabíola Attié de Castro;Yuetsu Tanaka;Osvaldo Massaiti Takayanagui;Dimas Tadeu Covas;Simone Kashima |
| Journal | kurdistan journal of applied research |
| Year | 2012 |
| DOI |
10.1590/S0074-02762012000600020
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.