safety of ovarian tissue autotransplantation for cancer patients

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ID: 212474
2012
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Abstract
Cancer treatments can induce premature ovarian failure in almost half of young women suffering from invasive neoplasia. Cryopreservation of ovarian cortex and subsequent autotransplantation of frozen-thawed tissue have emerged as promising alternatives to conventional fertility preservation technologies. However, human ovarian tissue is generally harvested before the administration of gonadotoxic treatment and could be contaminated with malignant cells. The safety of autotransplantation of ovarian cortex remains a major concern for fertility preservation units worldwide. This paper discusses the main tools for detecting disseminated cancer cells currently available, their limitations, and clinical relevance.
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bockstaele2012obstetricssafety Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Laurence Bockstaele;Sophie Tsepelidis;Julie Dechene;Yvon Englert;Isabelle Demeestere
Journal vìsnik nacìonalʹnogo avìacìjnogo unìversitetu
Year 2012
DOI
10.1155/2012/495142
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