bladder cancer screening among diabetic patients on metformin therapy in a west africa subregion
Clicks: 291
ID: 211902
2016
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
291 views
38 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #13 of 61 articles by views in Asian journal of psychiatry
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Objective: The use of certain medications among diabetic patients put them at risk of developing bladder cancer. This study was done to examine the effects of metformin therapy on the bladder of diabetic patients and to assess the correlation between the effects of metformin and its duration of therapy. Methods: A total of 150 diabetic patients were sampled using a cross sectional study design. 10-15mls of random urine samples were collected into sterile containers over a period of five weeks. Smears were prepared, fixed and stained using Papanicolaou staining method and examined under the microscope for cytological studies. Results: The probability of developing bladder cancer among diabetic patients on metformin therapy is 0% among participants of all categories: 99 females and 51 males partook in this study. Peak age group (35.33%) were between the ages of 51 to 60 years, least age group (4.67%) were 80 years and above. Traders of food items and used clothes constituted the peak occupational group of 27.52%, with fishermen as least occupation group(0.67%), age group 61 to 70 had the highest duration of therapy of (15.8%), the least duration of (4.625%) was among age group 25 to 30 years, the group of 80years and above had a duration of (4.857%). No inflammatory, degenerative, benign or malignant cells were observed among urine samples from diabetic patients on metformin. Conclusion: This study equips us with knowledge that metformin therapy has no direct influence on the development of cancer of the bladder among diabetic patients as observed through urine cytology. This is the first time such study is done in West Africa region. The clinical implication is that Metformin, the commonest prescribed oral hypoglycemic is safe when considering the carcinogenic effects of anti-diabetic drugs, unlike insulin and some other drugs which have carcinogenic potential.
Keywords: metformin; cancer; bladder; diabetes; therapy
| Reference Key |
fakpor2016advancesbladder
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Ufuoma Miller Fakpor;Ekpe Ekpe Lawson;Omotoso Ayodele Joshua |
| Journal | Asian journal of psychiatry |
| Year | 2016 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.