natriuretic peptides in kawasaki disease: the myocardial perspective

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ID: 211490
2013
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Abstract
Making a diagnosis of Kawasaki disease with certainty may be challenging, especially since the recognition of cases with incomplete diagnostic criteria and its consequences. In order to build the diagnostic case in daily practice, clinicians rely on clinical criteria established over four decades ago, aided by non specific laboratory tests, and above all inspired by experience. We have recently studied the diagnostic value of N-terminal pro B-type natriuretic peptide to improve the diagnostic certainty of cases with complete or incomplete clinical criteria. Our working hypothesis was based on the fact that myocarditis is present in nearly all Kawasaki disease patients supported by histology data. In this paper, we review these facts and the myocardial perspective from the diagnostic and the mechanistic standpoints.
Reference Key
dahdah2013diagnosticsnatriuretic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Nagib Dahdah;Anne Fournier
Journal Open forum infectious diseases
Year 2013
DOI
10.3390/diagnostics3010001
URL
http://www.mdpi.com/2075-4418/3/1/1
Keywords
diagnosis myocarditis kawasaki disease hyponatremia prognosismedicine (general)

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