the contribution of optical coherence tomography in neuromyelitis optica spectrum disorders

kontribusi tomografi koherensi optik pada gangguan spektrum neuromielitis optika

Clicks: 331
ID: 208706
2017
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #83 of 263 articles by views in journal of photochemistry and photobiology a: chemistry

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 263 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Neuromyelitis optica spectrum disorders (NMOSD) comprises a group of central nervous system disorders of inflammatory autoimmune origin that mainly affect the optic nerves and the spinal cord and can cause severe visual and general disability. The clinical signs are similar to those of multiple sclerosis (MS), with the result that it is often difficult to differentiate between the two, thus leading to misdiagnosis. As the treatment and prognosis of NMOSD and MS are different, it is important to make an accurate and early diagnosis of NMOSD. Optical coherence tomography (OCT) is a non-invasive technique that enables a quantitative study of the changes that the optic nerve and the macula undergo in several neurodegenerative diseases. Many studies have shown that some of these changes, such as retinal nerve fiber layer thinning or microcystic macular edema, can be related to alterations in the brain due to neurodegenerative disorders. The purpose of this mini-review is to show how OCT can be useful for the diagnosis of NMOSD and follow-up of affected patients, as well as for the differential diagnosis with MS.
*Neuromyelitis optica spectrum disorders* (NMOSD) mencakup sekelompok gangguan sistem saraf pusat yang disebabkan oleh proses inflamasi autoimun yang terutama memengaruhi saraf optik dan medula spinalis, serta dapat menyebabkan disabilitas visual dan umum yang berat. Tanda-tanda klinisnya serupa dengan sklerosis multipel (*multiple sclerosis*/MS), sehingga sering kali sulit untuk membedakan keduanya dan berujung pada kesalahan diagnosis. Mengingat tata laksana dan prognosis NMOSD dan MS berbeda, penegakan diagnosis NMOSD yang akurat dan dini menjadi sangat krusial. *Optical coherence tomography* (OCT) merupakan teknik noninvasif yang memungkinkan studi kuantitatif terhadap perubahan yang dialami saraf optik dan makula pada beberapa penyakit neurodegeneratif. Banyak penelitian telah menunjukkan bahwa beberapa perubahan ini, seperti penipisan lapisan serat saraf retina (*retinal nerve fiber layer*) atau edema makula mikrosistik, dapat berkaitan dengan perubahan pada otak akibat gangguan neurodegeneratif. Tujuan dari tinjauan ringkas ini adalah untuk menunjukkan bagaimana OCT dapat bermanfaat untuk diagnosis NMOSD dan pemantauan pasien yang terdampak, serta untuk diagnosis banding dengan MS.
Reference Key
mateo2017frontiersthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Javier Mateo, Olivia Esteban, Mireya Martínez, Andrzej Grzybowski, Francisco Javier Ascaso
Are you one of these authors? Claim your profile
Journal journal of photochemistry and photobiology a: chemistry
Year 2017
DOI
10.3389/fneur.2017.00493
URL
http://journal.frontiersin.org/article/10.3389/fneur.2017.00493/full
Keywords
Optical coherence tomography Autoimmune Diseases multiple sclerosis optic neuritis diseases of the nervous system devic diseaseneurology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.