mmrc dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
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2017
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Abstract
This study was undertaken to investigate idiopathic pulmonary fibrosis (IPF) patients' health-related quality of life (HRQoL) and symptoms in a real-life cross-sectional study. Our secondary aim was to create a simple identification method for patients with increased need for palliative care by studying the relationship between modified Medical Research Council (mMRC) dyspnoea scale, HRQoL and symptoms. We sent a self-rating HRQoL questionnaire (RAND-36) and modified Edmonton Symptom Assessment Scale (ESAS) to 300 IPF patients; 84% of the patients responded to these questionnaires. The most prevalent (>80%) symptoms were tiredness, breathlessness, cough and pain in movement. An increasing mMRC score showed a linear relationship (p<0.001) to impaired HRQoL in all dimensions of RAND-36 and the severity of all symptoms in ESAS. Dimensions of RAND-36 fell below general population reference values in patients with mMRC score ≥2. The intensity of pain in movement (p<0.001) and at rest (p=0.041), and the prevalence of chest pain (p<0.001) had a positive linear relationship to increased mMRC score. An increasing mMRC score reflects impaired HRQoL and a high symptom burden. In clinical practice, the mMRC scale could be used for screening and identification of IPF patients with increased need for palliative care.
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| Reference Key |
rajala2017erjmmrc
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|---|---|
| Authors | ;Kaisa Rajala;Juho T. Lehto;Eva Sutinen;Hannu Kautiainen;Marjukka Myllärniemi;Tiina Saarto |
| Journal | journal of bioscience and bioengineering |
| Year | 2017 |
| DOI |
10.1183/23120541.00084-2017
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| URL | |
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