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ID: 207494
2013
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Abstract
Toxic epidermal necrolysis is a rare, severe cutaneous reaction, mostly caused by drugs. It affects the skin and mucous membranes, with involvement of more than 30% of body surface. We describe the case of a young woman, previously healthy, who developed skin detachment of more than 90% of the body surface 15 days after being administered lansoprazole for peptic disease. The treatment consisted in discontinuation of the drug involved and early administration of intravenous human immunoglobulin, which led to a satisfactory outcome of the case, substantiating the impact of early diagnosis and treatment on the morbidity and mortality of these patients.
A Necrólise epidérmica tóxica é uma reação cutânea rara, causada principalmente por drogas. Envolve pele e mucosas, com acometimento superior a 30% da superfície corpórea. Ilustramos um caso de uma paciente jovem, previamente hígida que desenvolveu necrólise epidérmica tóxica, com descolamento superior a 90% da superfície corpórea, 15 dias após o início de lanzoprazol para doença péptica. O tratamento consistiu na interrupção do uso da droga implicada e administração precoce de imunoglobulina humana por via venosa, que levou a um desfecho satisfatório do caso, demonstrando o impacto do diagnóstico e tratamento precoces sobre a morbimortalidade destes pacientes.
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fracaroli2013anais Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Tainá Scalfoni Fracaroli;Ludmilla Queirós Miranda;João Luz Sodré;Mário Chaves;Alexandre Gripp
Journal Theriogenology
Year 2013
DOI
DOI not found
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000100117
Keywords
immunoglobulins intravenous

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