american cutaneous leishmaniasis with unusual clinical presentation and response to treatment
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ID: 205389
2016
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Abstract
The clinical manifestations and prognosis of cutaneous leishmaniasis (CL) can be influenced by the immune response of the patient and the species of the parasite. A case of atypical clinical presentation of CL, with development of non-characteristic lesions, poor response to therapy, and a long time to resolution is reported. Confirmatory laboratory tests included parasite detection, indirect immunofluorescence, Montenegro skin test, polymerase chain reaction, and parasite identification by multilocus enzyme electrophoresis. The parasite was identified as Leishmaniabraziliensis. The lesion was unresponsive to three complete courses of N-methylglucamine antimoniate intramuscular, and to treatment with pentamidine. The patient did not tolerate amphotericin B. The lesion finally receded after treatment with intravenous N-methylglucamine antimoniate. It is essential to ensure the accuracy of diagnosis and the appropriate treatment, which can include the use a second choice drug or a different route of administration.
| Reference Key |
fernandes2016revistaamerican
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|---|---|
| Authors | ;Andrea Claudia Bekner Silva FERNANDES;Raíssa Bocchi PEDROSO;Eneide Aparecida Sabaini VENAZZI;Paulo Donizeti ZANZARINI;Sandra Mara Alessi ARISTIDES;Maria Valdrinez Campana LONARDONI;Thaís Gomes Verzignassi SILVEIRA |
| Journal | 2017 12th international conference for internet technology and secured transactions, icitst 2017 |
| Year | 2016 |
| DOI |
10.1590/S1678-9946201658020
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| URL | |
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