therapeutic inertia in the new landscape of multiple sclerosis care

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ID: 203300
2018
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Abstract
The landscape of multiple sclerosis (MS) treatment is constantly changing. Significant heterogeneity exists in the efficacy and risks associated with these therapies. Therefore, clinicians have the challenge to tailor treatment based on several factors (disease activity level, risk of progression, individual patient preferences and characteristics, personal expertise, etc.), to identify the optimal balance between safety and efficacy. However, most clinicians have limited education in decision-making and formal training in risk management. Together, these factors may lead to therapeutic inertia (TI); defined as the absence of treatment initiation or intensification when therapeutic goals are unmet. TI may lead to suboptimal treatments choices, worse clinical outcomes, and more disability. This article provides a succinct overview on factors influencing TI in MS care.
Reference Key
saposnik2018frontierstherapeutic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Gustavo Saposnik;Gustavo Saposnik;Xavier Montalban;Xavier Montalban;Xavier Montalban
Journal journal of photochemistry and photobiology a: chemistry
Year 2018
DOI
10.3389/fneur.2018.00174
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