Synthesis and physicochemical properties of dual-responsive acrylic acid/butyl acrylate cross-linked nanogel systems.

Clicks: 267
ID: 20084
2019
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Abstract
A cross-linked amphiphilic nanogel containing a high mole% of hydrophilic pH-responsive moiety can provide enhanced functionality regarding stimuli-responsiveness, water-dispersibility, hydrophobic substance loading, and structural stability under harsh environmental conditions. These nanogels could be synthesized using a one-pot procedure for large-scale applications. Moreover, the interplay of various interaction forces in these colloidal systems is being investigated.Model nanogels consisting of acrylic acid-butyl acrylate-ethylene glycoldimethacrylate were synthesized using an emulsion copolymerization via a seeded semi-batch process under an acidic condition. The structures were assessed by Fourier transform infrared spectroscopy and potentiometric-conductometric titrations. Zeta potential, field-emission scanning electron microscopy, and transmission electron microscopy were used to evaluate the dispersion stability, size distribution, and structural distribution, respectively. Their stimuli-responsive behavior was studied by combining static and dynamic light scattering and titration analyses.Monodisperse nanospheres of approximately 150 nm were successfully prepared by implementing a one-pot practical pathway. These nanogels displayed a dual thermo- and pH-responsive behavior, reflecting the high efficiency of physical cross-linking make it ideal for drug delivery and oil industry applications. Moreover, a novel symmetric pH-activated morphology transformation behavior was revealed. Accordingly, a compositional distribution was proposed and assessed by exploring the polymerization process.
Reference Key
ashrafizadeh2019synthesisjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ashrafizadeh, Marjan;Tam, Kam Chiu;Javadi, Aliyar;Abdollahi, Mahdi;Sadeghnejad, Saeid;Bahramian, Alireza;
Journal Journal of colloid and interface science
Year 2019
DOI
S0021-9797(19)30967-1
URL
Keywords Keywords not found

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