Synthesis and physicochemical properties of dual-responsive acrylic acid/butyl acrylate cross-linked nanogel systems.
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ID: 20084
2019
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Abstract
A cross-linked amphiphilic nanogel containing a high mole% of hydrophilic pH-responsive moiety can provide enhanced functionality regarding stimuli-responsiveness, water-dispersibility, hydrophobic substance loading, and structural stability under harsh environmental conditions. These nanogels could be synthesized using a one-pot procedure for large-scale applications. Moreover, the interplay of various interaction forces in these colloidal systems is being investigated.Model nanogels consisting of acrylic acid-butyl acrylate-ethylene glycoldimethacrylate were synthesized using an emulsion copolymerization via a seeded semi-batch process under an acidic condition. The structures were assessed by Fourier transform infrared spectroscopy and potentiometric-conductometric titrations. Zeta potential, field-emission scanning electron microscopy, and transmission electron microscopy were used to evaluate the dispersion stability, size distribution, and structural distribution, respectively. Their stimuli-responsive behavior was studied by combining static and dynamic light scattering and titration analyses.Monodisperse nanospheres of approximately 150 nm were successfully prepared by implementing a one-pot practical pathway. These nanogels displayed a dual thermo- and pH-responsive behavior, reflecting the high efficiency of physical cross-linking make it ideal for drug delivery and oil industry applications. Moreover, a novel symmetric pH-activated morphology transformation behavior was revealed. Accordingly, a compositional distribution was proposed and assessed by exploring the polymerization process.
| Reference Key |
ashrafizadeh2019synthesisjournal
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| Authors | Ashrafizadeh, Marjan;Tam, Kam Chiu;Javadi, Aliyar;Abdollahi, Mahdi;Sadeghnejad, Saeid;Bahramian, Alireza; |
| Journal | Journal of colloid and interface science |
| Year | 2019 |
| DOI |
S0021-9797(19)30967-1
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| URL | |
| Keywords | Keywords not found |
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