lipid lowering activity of anthocephalus indicus root in hyperlipidemic rats
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ID: 200663
2010
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Abstract
The lipid lowering activity of Anthocephalus indicus (family Rubiaceae; Hindi name Kadamba) root extract has been studied in triton WR-1339 induced hyperlipidemia in rats. In this model, feeding with root extract (500 mg kg−1 b.w.) lowered plasma lipids and reactivated post-heparin lipolytic activity in hyperlipidemic rats. Furthermore, the root extract (50–500 μM) inhibited the generation of superoxide anions and hydroxyl radicals, in both enzymic and non-enzymic systems, in vitro. The results of the present study demonstrated both lipid lowering and antioxidant activities in root extract of A. indicus, which could help prevention of hyperlipidemia and related diseases.
| Reference Key |
kumar2010evidence-basedlipid
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|---|---|
| Authors | ;Vishnu Kumar;Mohammad Mubin Khan;Ashok Kumar Khanna;Ranjana Singh;Sushma Singh;Ramesh Chander;Farzana Mahdi;Abbas Ali Mahdi;Jitendra Kumar Saxena;Raj Kumar Singh |
| Journal | ACS applied materials & interfaces |
| Year | 2010 |
| DOI |
10.1093/ecam/nen001
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| URL | |
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