computer modeling of radiation effects

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ID: 200382
2007
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Ranked #121 of 292 articles by views in Proceedings of the National Academy of Sciences of the United States of America

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Abstract
Biological effects of low-dose radiation are studied by computational methods. Assessing the risks of low-dose radiation, i.e. radiation-induced cancer, is becoming important in the study of public health because of the many different types of exposures, medical exposures, and from radiation protection viewpoints. In general, radiation effects arise from damage done to DNA by ionizing radiation. Therefore, examining effects from the initial DNA damage to the risk assessment is a problem with a very wide spatiotemporal scale. We are studying this problem by dividing it into three parts: 1) the DNA strand is broken by ionizing radiation, 2) DNA lesion repair, and 3) the process of cell carcinogenesis and tumorigenesis. In this paper, we mainly focus on the third part, the study of modeling and simulation of cell carcinogenesis.
Reference Key
ouchi2007datacomputer Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;N B Ouchi
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 2007
DOI
10.2481/dsj.6.S278
URL
http://datascience.codata.org/articles/418
Keywords
model carcinogenesis computer simulation tumorigenesis

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