the role of il-1 family members and kupffer cells in liver regeneration
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ID: 199357
2016
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Abstract
Interleukin-1 (IL-1) family and Kupffer cells are linked with liver regeneration, but their precise roles remain unclear. IL-1 family members are pleiotropic factors with a range of biological roles in liver diseases, inducing hepatitis, cirrhosis, and hepatocellular carcinoma, as well as liver regeneration. Kupffer cells are the main source of IL-1 and IL-1 receptor antagonist (IL-1Ra), the key members of IL-1 family. This systemic review highlights a close association of IL-1 family members and Kupffer cells with liver regeneration, although their specific roles are inconclusive. Moreover, IL-1 members are proposed to induce effects on liver regeneration through Kupffer cells.
| Reference Key |
tan2016biomedthe
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| Authors | ;Quanhui Tan;Jianjun Hu;Xiaolan Yu;Wen Guan;Huili Lu;Yan Yu;Yongsheng Yu;Guoqiang Zang;Zhenghao Tang |
| Journal | spectrochimica acta - part a: molecular and biomolecular spectroscopy |
| Year | 2016 |
| DOI |
10.1155/2016/6495793
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| URL | |
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