Chitosan Modification and Pharmaceutical/Biomedical Applications

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ID: 19934
2010
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Abstract
Chitosan has received much attention as a functional biopolymer for diverse applications, especially in pharmaceutics and medicine. Our recent efforts focused on the chemical and biological modification of chitosan in order to increase its solubility in aqueous solutions and absorbability in the in vivo system, thus for a better use of chitosan. This review summarizes chitosan modification and its pharmaceutical/biomedical applications based on our achievements as well as the domestic and overseas developments: (1) enzymatic preparation of low molecular weight chitosans/chitooligosaccharides with their hypocholesterolemic and immuno-modulating effects; (2) the effects of chitin, chitosan and their derivatives on blood hemostasis; and (3) synthesis of a non-toxic ion ligand—D-Glucosaminic acid from Oxidation of D-Glucosamine for cancer and diabetes therapy.
Reference Key
zhang2010chitosanmarine Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhang, Jiali;Xia, Wenshui;Liu, Ping;Cheng, Qinyuan;Tahi, Talba;Gu, Wenxiu;Li, Bo;
Journal Marine drugs
Year 2010
DOI
DOI not found
URL
http://www.mdpi.com/1660-3397/8/7/1962/
Keywords Keywords not found

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