cannabidiol as a promising strategy to treat and prevent movement disorders?

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ID: 198583
2018
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Abstract
Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating conditions linked to oxidative stress and neurodegeneration. When available, the pharmacological therapies for these disorders are still mainly symptomatic, do not benefit all patients and induce severe side effects. Cannabidiol is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. Although the studies that investigate the effects of this compound on movement disorders are surprisingly few, cannabidiol emerges as a promising compound to treat and/or prevent them. Here, we review these clinical and pre-clinical studies and draw attention to the potential of cannabidiol in this field.
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Authors ;Fernanda F. Peres;Fernanda F. Peres;Alvaro C. Lima;Jaime E. C. Hallak;Jaime E. C. Hallak;José A. Crippa;José A. Crippa;Regina H. Silva;Vanessa C. Abílio;Vanessa C. Abílio
Journal chemical research in chinese universities
Year 2018
DOI
10.3389/fphar.2018.00482
URL
http://journal.frontiersin.org/article/10.3389/fphar.2018.00482/full
Keywords
Prevention movement disorders schizophrenia parkinson's disease side effects cannabidiol huntington's disease pharmacology

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