preparação de derivados do lapachol em meio ácido e em meio básico: uma proposta de experimentos para a disciplina de química orgânica experimental
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ID: 198513
2013
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Abstract
In this educational paper we describe the extraction of lapachol from its natural source according to acid-base concepts in organic chemistry and the use of its derivatives β-lapachone and hydroxy-hydrolapachol to exemplify intramolecular cyclization, carbocation stability, Michael addition reaction and chromatography. The experiments were performed during three different undergraduate organic chemistry laboratory classes using low cost material, while avoiding color reagents for TLC visualization, as well as small-scale column chromatography to isolate the mixture of lapachol and β-lapachone.
| Reference Key |
barbosa2013qumicapreparao
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|---|---|
| Authors | ;Ticiano Pereira Barbosa;Hermes Diniz Neto |
| Journal | greece and rome |
| Year | 2013 |
| DOI |
10.1590/S0100-40422013000200021
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| URL | |
| Keywords | Keywords not found |
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