Cichorins D-F: Three New Compounds from and Their Biological Effects.
Clicks: 298
ID: 198025
2020
Article Quality & Performance Metrics
Overall Quality
Improving Quality
0.0
/100
Combines engagement data with AI-assessed academic quality
Reader Engagement
Emerging Content
0.3
/100
1 views
1 readers
Trending
AI Quality Assessment
Not analyzed
Abstract
L., (chicory) is employed in various traditional medicines to treat a wide range of diseases and disorders. In the current investigation, two new naphthalane derivatives viz., cichorins D () and E (), along with one new anthraquinone cichorin F (), were isolated from In addition, three previously reported compounds viz., β-sitosterol (), β-sitosterol β-glucopyranoside (), and stigmasterol () were also isolated from Their structures were established via extensive spectroscopic data, including 1D (H and C) and 2D NMR (COSY, HSQC and HMBC), and ESIMS. Cichorin E () has a weak cytotoxic effect on breast cancer cells (MDA-MB-468: IC: 85.9 µM) and Ewing's sarcoma cells (SK-N-MC: IC: 71.1 µM); cichorin F () also illustrated weak cytotoxic effects on breast cancer cells (MDA-MB-468: IC: 41.0 µM and MDA-MB-231: IC: 45.6 µM), and SK-N-MC cells (IC: 71.9 µM). Moreover compounds - did not show any promising anthelmintic effects.
| Reference Key |
khan2020cichorinsmolecules
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Khan, Muhammad Farooq;Nasr, Fahd A;Noman, Omar M;Alyhya, Nouf Abdulaziz;Ali, Iftikhar;Saoud, Mohamad;Rennert, Robert;Dube, Mthandazo;Hussain, Wahid;Green, Ivan R;Basudan, Omer Ahmed M;Ullah, Riaz;Anazi, Shamsa Hilal;Hussain, Hidayat; |
| Journal | molecules |
| Year | 2020 |
| DOI |
E4160
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.