self-reported quality of life in patients with retinitis pigmentosa and maculopathy of bothnia type
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2010
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Abstract
Marie SI Burstedt, Eva MönestamDepartment of Clinical Sciences/Ophthalmology, University of Umeå, SwedenPurpose: To assess vision-related quality-of-life subscales with objective measurements of visual function in patients affected with retinitis pigmentosa of Bothnia type (BD).Methods: Forty-nine patients answered the NEI-VFQ-25 questionnaire. High- and low-contrast distance acuity (VA), near VA, and visual fields (VF) were measured. Weighted VA (WVA) and low-contrast (10%) VA (WLCVA), binocular VF areas, and central scotoma were calculated. Adjusted mean subscale scores were calculated and associations analyzed.Results: Subscale scores for general, far, and near vision, social functioning, and color vision were lowest while general health, ocular pain, and mental health were highest in the BD phenotype. The correlations were substantial and similar for WVA, WLCVA, and near vision. The degree of measured VF impairment had few associations with the different adjusted subscale scores.Conclusion: The NEI VFQ-25 subscales were well associated with clinical vision measures depending on VA. The progression of VF defects typical for the BD phenotype does not seem to affect the self-perceived quality of life, which might indicate adaptability to this type of progressive VF loss. The BD phenotype has a significant impact on multiple domains of daily life, but there are no signs of accelerating depression related to the increasing visual impairment.Keywords: visual function, low vision, maculopathy, RP, Bothnia dystrophy, visual cycle, RLBP1
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burstedt2010clinicalself-reported
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| Authors | ;Marie SI Burstedt;Eva Mönestam |
| Journal | e3s web of conferences |
| Year | 2010 |
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