methyl alcohol poisoning: an autopsy study of 28 cases.

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ID: 196556
1991
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Abstract
Twenty eight fatal cases out of the 97 cases of methyl alcohol (MA) poisoning admitted to K. E. M. Hospital in August 1988 during a single outbreak were studied. The latent period between consumption of the drink and development of symptoms was variable (range 7 1/2 hours to 60 hours). CNS symptoms were predominant (75% of cases) and shock either at admission or as a late event was seen in 89% of the cases. Blurring of vision was seen in 42.8% and blindness in 10.7% of cases. Minimum fatal period was 7 1/2 hours and maximum was 12 days. Methanol levels in blood and viscera were variable (average 155.8 mg%, max. 420.4 mg%). In 4 cases, significant amount of MA was detected in stomach contents 5-12 days after consumption of MA, raising the question of resecretion of MA in stomach. Shrinkage and degeneration of neurons in the parietal cortex was seen in 85.7% of cases. Putamental degeneration and necrosis was seen in 7.14%. Haemorrhage (3.5%) and sponginess (7.14%) was observed in the optic chiasma. Severe renal tubular degeneration and patchy necrosis was seen in all cases. Fatty changes (67.8%) and microvesicular fat (42.5%) were seen in the hepatocytes.
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b1991journalmethyl Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Mittal B;Desai A;Khade K
Journal international islamic university malaysia engineering journal
Year 1991
DOI
DOI not found
URL
http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1991;volume=37;issue=1;spage=9;epage=13;aulast=Mittal
Keywords
analysis Epidemiology adult india human autopsy aged female poisoning disease outbreaks male comparative study methanol middle age pathologymedicine

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