cephradine-a new cephalosporin in recurrent urinary tract infection

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ID: 196060
1977
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Abstract
Out of 866 bacterial isolates grown in significant colony counts from 3 consecutive mid-stream urine samples or from a single sample of urine obtained by suprapubic bladder puncture, 305 isolates (35.22%) were found to be sensitive to Cephradine. It was noted that Gram positive organisms (63.44%) manifested highest sensitivity to this antibiotic. Next in order was E. coli with a sensitivity of 60.54%. The clinical trial revealed a good response in 59.37% and 81.81; of patients with oral and injectable group re-spectively. The maximum response was seen in E. coli infections (89.47%) and Gram positive organisms coming next with 80% re-sponse. No major untoward reactions were noted in patients with or without azotaemia and the antibiotic could be used safely even in presence of renal failure.
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Authors ;Acharya Vidya;Shroff Kamini;Mehta Neela;Patel K;Jadav Surangi
Journal international islamic university malaysia engineering journal
Year 1977
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