The disruption of verM activates the production of gliocladiosin A and B in Clonostachys rogersoniana.

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ID: 1939
2019
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Abstract
Gliocladiosin A (1) and B (2), two dipeptides conjugated with macrolides, were identified from a verM disruption mutant of the Cordycep-colonizing fungus Clonostachys rogersoniana. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic data analysis, including MS, NMR, CD and X-ray diffraction. A biogenetic pathway for 1 and 2 was proposed. These two compounds showed moderate antibacterial effects.
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wang2019theorganic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Wang, Ying;Ren, Jinwei;Li, Honghua;Pan, Yuanyuan;Liu, Xingzhong;Che, Yongsheng;Liu, Gang;
Journal Organic & biomolecular chemistry
Year 2019
DOI
10.1039/c9ob01102a
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