seropositivity and risk factors of hepatitis b in maharashtra, india
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ID: 193241
2016
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Abstract
Background: Hepatitis B is one of the most important
infectious diseases worldwide. More than 240 million
people have chronic (long term) liver infections. More
than 780 000 people die every year due to
complications of hepatitis B, including cirrhosis and
liver cancer. Hepatitis B is a major public health
problem in India. The average carrier rate of Hepatitis
B Virus (HBV) in general population is considered to
be approximately 4%. Aim and Objective: To estimate
the seropositivity and to understand dynamics of HBV
transmission. Material and Methods: The study was
conducted from March 2010 to September 2012.
Seropositivity of Hepatitis B surface antigen among
hospital based general population was determined
using a third generation ELISA in the Department of
Microbiology, Krishna Institute of Medical Sciences,
Karad, Maharashtra, India. A total of 25193 serum
samples were screened for HBV infection. Results:
Out of 25193 samples screened 473(1.87%) serum
samples were positive for HBsAg. The mean age of
HBsAg positive patient was 40.71 ± 17.46 and mean
age of HBsAg negative patients was 34.03 ± 17.51.
Prevalence of hepatitis B infection was signicantly
higher in patients with history of blood transfusion,
tattooing, skin and ear piercing, history of dialysis,
habit of alcohol, habit of tobacco and occupation.
Conclusion: There is limited data about blood borne
hepatitis i.e. Hepatitis B and Hepatitis C in Western
Maharashtra. For prevention and control of hepatitis B
raising awareness, promoting prevention of
transmission through vaccination, safe injection
practices and blood safety and promoting wider access
to monitoring, screening, care and treatment services is
necessary
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| Authors | ;S. R. Patil;S. S. Patil;G.S. Karande;H. V. Patil;P. M. Mane |
| Journal | The Cochrane database of systematic reviews |
| Year | 2016 |
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