synthesis of conformationally constrained aryl- or heteroarylpiperazinyl derivatives of selected imides as 5-ht1a receptor ligands
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ID: 193167
2006
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Abstract
The preparation of a number of cyclic imide 5-HT1A receptor ligandderivatives has been described. Their structures were conformationally constrained byintroducing rigid linkers containing unsaturated bonds or aromatic benzene rings. Thesecompounds are expected to possess anxiolytic and antidepressant activity.
| Reference Key |
kuran2006moleculessynthesis
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|---|---|
| Authors | ;Bożena Kuran;Mariola Krawiecka;Jerzy Kossakowski |
| Journal | Journal of ethnopharmacology |
| Year | 2006 |
| DOI |
10.3390/11080615
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| URL | |
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