retinal nerve fiber layer decrease during glycemic control in type 2 diabetes
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ID: 192726
2010
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Abstract
Purpose. To assess an effect of glycemic control on retinal nerve fiber layer (RNFL) in type 2 diabetes mellitus.
Methods. Thirty-eight eyes of 38 patients with type 2 diabetes undergoing blood glucose regulation were enrolled. All patients were examined at (1) initial visit, (2) 1 month, (3) 2 months, and (4) 4-month after the initial examination. On each occasion, glycosylated hemoglobin (HbA1c) levels and optical coherence tomography (OCT) scanning for RNFL thickness were evaluated. 360 degree circular OCT scans with a diameter of 3.4 mm centered on the optic disc were performed.
Results. Significant RNFL decrease was seen in the superior area between initial and 4 months examination (𝑃=.043). The relationship between the changes in HbA1c and the changes in RNFL thickness was observed in superior, temporal, and inferior area (𝑃<.05) at 4 months. Conclusions. This study suggests that the glycemic control affects RNFL within 4 months.
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| Reference Key |
sugimoto2010journalretinal
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|---|---|
| Authors | ;Masahiko Sugimoto;Mikio Sasoh;Masashi Ido;Chisato Narushima;Yukitaka Uji |
| Journal | chemical reviews |
| Year | 2010 |
| DOI |
10.1155/2010/569215
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| URL | |
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